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STANOTREX – 5mg – 100 Tab.

Stanozolol 5 mg/tab

100 Tablets For oral use

Therapeutic Class: Anabolic Agent

Composition:

Each tablet of STANOTREX contains:

  • 5 mg Stanozolol

Description

Stanozolol 5 mg/tab

100 Tablets For oral use

Therapeutic Class: Anabolic Agent

Composition:

Each tablet of STANOTREX contains:

  • 5 mg Stanozolol

Indication & Dosage:

Stanozolol is used in the treatment of hereditary angioedema, which causes episodes of swelling of the face, extremities, genitals, bowel wall, and throat. Stanozolol may decrease the frequency and severity of these attacks.

Oral

Vascular manifestations of Behcet’s syndrome

Adult: 10 mg daily.

Hereditary angioedema

Initially, 2.5-10 mg daily, reduced according to response. Maintenance: 2 mg daily or on alternate days or 2.5 mg 3 times wkly. Child: <6 yr: 1 mg daily; 6-12 yr: Up to 2 mg daily.

Contraindications:

Heart or blood vessel disease; had a heart attack; a high level of cholesterol in the blood; bleeding or blood clotting problems; diabetes; using oral anticoagulant (blood thinner); liver problems; or kidney problems Pregnancy and lactation; carcinoma of prostate or breast in men, hypercalcaemia, hypercalciuria, porphyria, severe hepatic impairment.

Special Precautions:

Patients with cardiac, renal or hepatic disease, epilepsy or OM. Children, elderly.

Monitor liver function, haematocrit and haemoglobin concentrations. Not recommended for treatment of hereditary angioedema in premenopausal women.

Adverse Drug Reactions:

In rare cases, serious and even fatal cases of liver problems have developed during treatment with stanozolol. Contact your doctor immediately if you experience abdominal pain, light colored stools, dark colored urine, unusual fatigue, nausea or vomiting, or yellowing of the skin or eyes. These may be early signs of liver problems.

If you experience any of the following serious side effects, contact your doctor immediately or seek emergency medical attention:an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); swelling of the arms or legs (especially ankles); frequent or persistent erections, or breast tenderness or enlargement (male patients); orvoice changes (hoarseness, deepening), hair loss, facial hair growth, clitoral enlargement, or menstrual irregularities (female patients).

Other less serious side effects may also occur. Talk to your doctor if you experience new or worsening acne;difficulty sleeping;headache; orchanges in sexual desire.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Drug Interactions:

Enhances activity of insulin, sulfonylureas, levothyroxine and anticoagulants e.g. warfarin. May cause resistance to the effects of neuromuscular blockers.

Potentially Fatal: Enhances activity of insulin, sulfonylureas, levothyroxine and anticoagulants e.g. warfarin. May cause resistance to the effects of neuromuscular blockers.

Pregnancy Category:

Category X: Studies in animals or human beings have demonstrated foetal abnormalities or there is evidence of foetal risk based on human experience or both, and the risk of the use of the drug in pregnant women clearly outweighs any possible benefit. The drug is contraindicated in women who are or may become pregnant.

Mechanism of Action:

Stanozolol is a structural analogue of testosterone which increases collagen production and dec_reases the anti-anabolic action of cortisone. It is also reported to reduce fibrin deposition. It corrects the formation of kinin or kinin-like factors which may be associated with oedema and swelling seen in hereditary angioedema.

Metabolism: Hepatic.

Excretion: Urine (90%), faeces (6%).

Storage:

Store at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly-closed container. Store away from heat, moisture, and light.

Do not store in the bathroom. Keep out of the reach of children and away from pets.

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